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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK2 All Species: 33.94
Human Site: Y194 Identified Species: 62.22
UniProt: Q13177 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13177 NP_002568.2 524 58043 Y194 P D H T K S I Y T R S V I D P
Chimpanzee Pan troglodytes XP_516976 524 58004 Y194 P D H T K S I Y T R S V I D P
Rhesus Macaque Macaca mulatta XP_001099936 524 57950 Y194 P D H T K S I Y T R S V I D P
Dog Lupus familis XP_849432 524 57951 Y194 P D H T K S I Y T R S V I D P
Cat Felis silvestris
Mouse Mus musculus Q8CIN4 524 57912 Y194 P D H T K S I Y T R S V I D P
Rat Rattus norvegicus Q64303 524 57942 Y194 P D H T K S I Y T R S V I D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422671 521 57527 Y191 P D H T K S I Y T R S V I D P
Frog Xenopus laevis NP_001083738 517 57265 Y189 P E H T K S M Y T R S V I D P
Zebra Danio Brachydanio rerio NP_001020627 539 59696 R209 H T K S V Y T R P S V I D P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S313 Q H L A K S A S R A S S S S G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17850 572 63863 S240 D R P A R T L S I Y T K P K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 A565 Q V A Q S P K A P A Q E T V T
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 H619 P P T S Q H Q H P R Q P D I N
Conservation
Percent
Protein Identity: 100 99.6 99 96.7 N.A. 97.1 96.9 N.A. N.A. 92.7 87.2 83.8 N.A. 34.4 N.A. 53.3 N.A.
Protein Similarity: 100 99.6 99.2 98.2 N.A. 98.4 98.2 N.A. N.A. 95.6 92.5 89 N.A. 50.5 N.A. 68.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 86.6 0 N.A. 20 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 13.3 N.A. 20 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32 32.6
Protein Similarity: N.A. N.A. N.A. N.A. 42.4 42.3
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 0 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 16 0 0 8 8 0 16 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 54 0 0 0 0 0 0 0 0 0 0 16 62 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 8 8 62 0 0 8 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 54 0 8 0 0 8 62 8 0 % I
% Lys: 0 0 8 0 70 0 8 0 0 0 0 8 0 8 0 % K
% Leu: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 70 8 8 0 0 8 0 0 24 0 0 8 8 8 62 % P
% Gln: 16 0 0 8 8 0 8 0 0 0 16 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 8 8 70 0 0 0 0 0 % R
% Ser: 0 0 0 16 8 70 0 16 0 8 70 8 8 8 0 % S
% Thr: 0 8 8 62 0 8 8 0 62 0 8 0 8 0 8 % T
% Val: 0 8 0 0 8 0 0 0 0 0 8 62 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 62 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _